Zur Startseite gehen
0,00 €*
Cover: 9781493993222 | Immunotoxicity Testing | Methods and Protocols | DeWitt (u. a.) | Buch
Dekorationsartikel gehören nicht zum Leistungsumfang.
Immunotoxicity Testing
Methods and Protocols
Taschenbuch von Jamie C. DeWitt (u. a.)
Sprache: Englisch

151,95 €*

inkl. MwSt.

Versandkostenfrei per Post / DHL

Lieferzeit 4-7 Werktage

Kategorien:
Beschreibung
This fully updated volume utilizes the expertise of scientists currently engaged in immunotoxicity testing to provide the reader with lab-ready procedures and the background information needed to identify effective testing approaches. Dedicated to identifying and describing exogenous agents that can modify immune function, uncovering modes and mechanisms of action for such agents, and translating data from the laboratory and from the clinic to better predict health risks as well as benefits to those who are exposed to immunomodulatory agents, immunotoxicity testing continues to be a vital field of study, and this collection highlights both the ¿tried and true¿ methods as well as alternative protocols that have been more recently developed. Written in the highly successful Methods in Molecular Biology format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, andtips on troubleshooting and avoiding known pitfalls.
Authoritative and practical, Immunotoxicity Testing: Methods and Protocols, Second Edition serves as a valuable contribution to the continued evolution and the application of immunotoxicity testing.
This fully updated volume utilizes the expertise of scientists currently engaged in immunotoxicity testing to provide the reader with lab-ready procedures and the background information needed to identify effective testing approaches. Dedicated to identifying and describing exogenous agents that can modify immune function, uncovering modes and mechanisms of action for such agents, and translating data from the laboratory and from the clinic to better predict health risks as well as benefits to those who are exposed to immunomodulatory agents, immunotoxicity testing continues to be a vital field of study, and this collection highlights both the ¿tried and true¿ methods as well as alternative protocols that have been more recently developed. Written in the highly successful Methods in Molecular Biology format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, andtips on troubleshooting and avoiding known pitfalls.
Authoritative and practical, Immunotoxicity Testing: Methods and Protocols, Second Edition serves as a valuable contribution to the continued evolution and the application of immunotoxicity testing.
Zusammenfassung

Includes cutting-edge techniques for the study of immunotoxicity testing

Provides step-by-step detail essential for reproducible results

Contains key implementation advice from the experts

Inhaltsverzeichnis
Immunotoxicology: A Brief History.- Clinical Immunotoxicology.- Investigative Immunotoxicology.- Developmental Immunotoxicity (DIT) Testing: Current Recommendations and the Future of DIT Testing.- Markers of Inflammation.- The Sheep Erythrocyte T-Dependent Antibody Response (TDAR).- Methylated-Bovine Serum Albumin (mBSA)-Induced Delayed-Type Hypersensitivity in Mice.- Use of the LLNA:BrdU-ELISA for Skin Sensitization Hazard Assessment.- Host Resistance Assays.- Enhanced Histopathology Evaluation of Lymphoid Organs.- Tumor Challenges in Immunotoxicity Testing.- Flow Cytometry for the Immunotoxicologist.- Evaluation of Cell-Mediated Immune Function Using the Cytotoxic T Lymphocyte Assay.- Evaluation of Cell Proliferation and Apoptosis in Immunotoxicity Testing.- Natural Killer (NK) Cell Assays in Immunotoxicity Testing.- Dendritic Cell Assays.- Evaluating Macrophages in Immunotoxicity Testing.- Evaluating Cytokines in Immunotoxicity Testing.- Functional Assays of Hematopoietic Stem Cellsin Toxicology Research.- CD4
+
T Cell Differentiation and Activation.- Isolation and Identification of Innate Lymphoid Cells (ILCs) for Immunotoxicity Testing.- Evaluating Antigen-Specific IgE Using the Rat Basophil Leukemia Cell (RBL) Assay.- Challenges for Integrating Immunotoxicology into the 21
st
Century Toxicology Testing Paradigm.
Details
Erscheinungsjahr: 2019
Fachbereich: Toxikologie
Genre: Importe, Medizin
Rubrik: Wissenschaften
Medium: Taschenbuch
Reihe: Methods in Molecular Biology
Inhalt: xiii
412 S.
18 s/w Illustr.
23 farbige Illustr.
412 p. 41 illus.
23 illus. in color.
ISBN-13: 9781493993222
ISBN-10: 1493993224
Sprache: Englisch
Ausstattung / Beilage: Paperback
Einband: Kartoniert / Broschiert
Redaktion: DeWitt, Jamie C.
Bowman, Christal C.
Rockwell, Cheryl E.
Herausgeber: Jamie C DeWitt/Cheryl E Rockwell/Christal C Bowman
Auflage: Softcover reprint of the original 2nd ed. 2018
Hersteller: Springer New York
Springer US, New York, N.Y.
Methods in Molecular Biology
Verantwortliche Person für die EU: Books on Demand GmbH, In de Tarpen 42, D-22848 Norderstedt, info@bod.de
Maße: 254 x 178 x 24 mm
Von/Mit: Jamie C. DeWitt (u. a.)
Erscheinungsdatum: 25.07.2019
Gewicht: 0,8 kg
Artikel-ID: 116615438
Zusammenfassung

Includes cutting-edge techniques for the study of immunotoxicity testing

Provides step-by-step detail essential for reproducible results

Contains key implementation advice from the experts

Inhaltsverzeichnis
Immunotoxicology: A Brief History.- Clinical Immunotoxicology.- Investigative Immunotoxicology.- Developmental Immunotoxicity (DIT) Testing: Current Recommendations and the Future of DIT Testing.- Markers of Inflammation.- The Sheep Erythrocyte T-Dependent Antibody Response (TDAR).- Methylated-Bovine Serum Albumin (mBSA)-Induced Delayed-Type Hypersensitivity in Mice.- Use of the LLNA:BrdU-ELISA for Skin Sensitization Hazard Assessment.- Host Resistance Assays.- Enhanced Histopathology Evaluation of Lymphoid Organs.- Tumor Challenges in Immunotoxicity Testing.- Flow Cytometry for the Immunotoxicologist.- Evaluation of Cell-Mediated Immune Function Using the Cytotoxic T Lymphocyte Assay.- Evaluation of Cell Proliferation and Apoptosis in Immunotoxicity Testing.- Natural Killer (NK) Cell Assays in Immunotoxicity Testing.- Dendritic Cell Assays.- Evaluating Macrophages in Immunotoxicity Testing.- Evaluating Cytokines in Immunotoxicity Testing.- Functional Assays of Hematopoietic Stem Cellsin Toxicology Research.- CD4
+
T Cell Differentiation and Activation.- Isolation and Identification of Innate Lymphoid Cells (ILCs) for Immunotoxicity Testing.- Evaluating Antigen-Specific IgE Using the Rat Basophil Leukemia Cell (RBL) Assay.- Challenges for Integrating Immunotoxicology into the 21
st
Century Toxicology Testing Paradigm.
Details
Erscheinungsjahr: 2019
Fachbereich: Toxikologie
Genre: Importe, Medizin
Rubrik: Wissenschaften
Medium: Taschenbuch
Reihe: Methods in Molecular Biology
Inhalt: xiii
412 S.
18 s/w Illustr.
23 farbige Illustr.
412 p. 41 illus.
23 illus. in color.
ISBN-13: 9781493993222
ISBN-10: 1493993224
Sprache: Englisch
Ausstattung / Beilage: Paperback
Einband: Kartoniert / Broschiert
Redaktion: DeWitt, Jamie C.
Bowman, Christal C.
Rockwell, Cheryl E.
Herausgeber: Jamie C DeWitt/Cheryl E Rockwell/Christal C Bowman
Auflage: Softcover reprint of the original 2nd ed. 2018
Hersteller: Springer New York
Springer US, New York, N.Y.
Methods in Molecular Biology
Verantwortliche Person für die EU: Books on Demand GmbH, In de Tarpen 42, D-22848 Norderstedt, info@bod.de
Maße: 254 x 178 x 24 mm
Von/Mit: Jamie C. DeWitt (u. a.)
Erscheinungsdatum: 25.07.2019
Gewicht: 0,8 kg
Artikel-ID: 116615438
Sicherheitshinweis

Ähnliche Produkte

Diese Website verwendet Cookies, um eine bestmögliche Erfahrung bieten zu können. Mehr Informationen ...