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Cover: 9783030939892 | Advances in Hemophilia Treatment | From Genetics to Joint Health
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Advances in Hemophilia Treatment
From Genetics to Joint Health
Buch von E. Carlos Rodríguez-Merchán
Sprache: Englisch

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Beschreibung
This book offers a comprehensive and state of the art overview of hemophilia management by reviewing all most recent advances and cutting edge information in this fast evolving field. As hemophilia patients are often affected by joint problems it also provides clear guidance on the surgical treatment of musculo-skeletal manifestations.

The first part is devoted to the disease¿s pathophysiology (differentiating hemophilia A and B), genetics, pharmacotherapy ¿ including replacement and non-replacement therapy ¿ and gene therapy, as well as quality of life issues ¿ also related to hemophilia carriers. The second part is then focused on joint problems, ranging from joint health assessment and pain control to surgical treatment of acute hemarthrosis and hemophilic arthropathy, i.e. radiosynovectomy, total joint arthroplasty and arthroscopic joint debridement.
Written by experts drawn from leading institutions involved in treatment of hemophilia andrelated joint problems, this book offers a valuable resource to hematologists, orthopedic surgeons, rehabilitation physicians, radiologists, and pharmacy researchers.
This book offers a comprehensive and state of the art overview of hemophilia management by reviewing all most recent advances and cutting edge information in this fast evolving field. As hemophilia patients are often affected by joint problems it also provides clear guidance on the surgical treatment of musculo-skeletal manifestations.

The first part is devoted to the disease¿s pathophysiology (differentiating hemophilia A and B), genetics, pharmacotherapy ¿ including replacement and non-replacement therapy ¿ and gene therapy, as well as quality of life issues ¿ also related to hemophilia carriers. The second part is then focused on joint problems, ranging from joint health assessment and pain control to surgical treatment of acute hemarthrosis and hemophilic arthropathy, i.e. radiosynovectomy, total joint arthroplasty and arthroscopic joint debridement.
Written by experts drawn from leading institutions involved in treatment of hemophilia andrelated joint problems, this book offers a valuable resource to hematologists, orthopedic surgeons, rehabilitation physicians, radiologists, and pharmacy researchers.
Über den Autor

E. Carlos Rodríguez-Merchán is a Specialist in Orthopedic Surgery and "Emeritus" Consultant Orthopedic Surgeon currently working at the Department of Orthopedic Surgery, La Paz University Hospital, Madrid, Spain. Dr. Rodríguez-Merchán graduated from Complutense University with a degree in Medicine and Surgery in 1974, and subsequently completed a PhD in Medicine and Surgery. He is a former Associate Professor of Orthopedics at the Autonomous University of Madrid. Dr. Rodríguez-Merchán is the author of more than 300 articles in peer-reviewed PubMed-cited journals, as well as 11 books.

Zusammenfassung

Offers a state of the art overview of hemophilia management and related joint problems

Cats new light on hemophilia's pathophysiology, genetics, pharmacotherapy and gene therapy

Written by experts from the leading institution involved in treatment of hemophilia and related joint problems

Inhaltsverzeichnis
1. Pathophysiology of hemophilia.- 2. Genetics of Hemophilia A and B.- 3. Inhibitors in Hemophilia A.- 4. Immune Tolerance In Patients with Hemophilia A.- 5. Hemophilia A: New drugs.- 6. Inhibitors in Hemophilia B.- 7. Immune Tolerance Induction in Hemophilia B.- 8. Hemophilia B: New Drugs.- 9. Management of Hemophilia Carriers.- 10. Pharmacoeconomic Aspects in Hemophilia.- 11. Assessment of Joint Health and Outcome Measures in Hemophilia.- 12. Musculoskeletal Medicine in Hemophilia.- 13. Management of Acute Hemarthrosis in Hemophilia (Including Joint Aspiration).- 14. Hemophilic Arthropathy: Radiosynovectomy.- 15. Hemophilic Arthropathy: Arthroscopic Joint Debridement.- 16. Hemophilic Arthropathy: Total Joint Arthroplasty.- 17. Hemophilic Arthropathy: Other Orthopedic Procedures.- 18. Gene Therapy in Hemophilia: Latest Advances.- 19.A Summary of the Recent Recommendations of the WFH.
Details
Erscheinungsjahr: 2022
Fachbereich: Andere Fachgebiete
Genre: Mathematik, Medizin, Naturwissenschaften, Technik
Rubrik: Wissenschaften
Medium: Buch
Inhalt: viii
173 S.
11 s/w Illustr.
31 farbige Illustr.
173 p. 42 illus.
31 illus. in color.
ISBN-13: 9783030939892
ISBN-10: 3030939898
Sprache: Englisch
Ausstattung / Beilage: HC runder Rücken kaschiert
Einband: Gebunden
Redaktion: Rodríguez-Merchán, E. Carlos
Herausgeber: E Carlos Rodríguez-Merchán
Auflage: 1st ed. 2022
Hersteller: Springer International Publishing
Springer International Publishing AG
Verantwortliche Person für die EU: Books on Demand GmbH, In de Tarpen 42, D-22848 Norderstedt, info@bod.de
Maße: 260 x 183 x 16 mm
Von/Mit: E. Carlos Rodríguez-Merchán
Erscheinungsdatum: 23.04.2022
Gewicht: 0,596 kg
Artikel-ID: 120855741
Über den Autor

E. Carlos Rodríguez-Merchán is a Specialist in Orthopedic Surgery and "Emeritus" Consultant Orthopedic Surgeon currently working at the Department of Orthopedic Surgery, La Paz University Hospital, Madrid, Spain. Dr. Rodríguez-Merchán graduated from Complutense University with a degree in Medicine and Surgery in 1974, and subsequently completed a PhD in Medicine and Surgery. He is a former Associate Professor of Orthopedics at the Autonomous University of Madrid. Dr. Rodríguez-Merchán is the author of more than 300 articles in peer-reviewed PubMed-cited journals, as well as 11 books.

Zusammenfassung

Offers a state of the art overview of hemophilia management and related joint problems

Cats new light on hemophilia's pathophysiology, genetics, pharmacotherapy and gene therapy

Written by experts from the leading institution involved in treatment of hemophilia and related joint problems

Inhaltsverzeichnis
1. Pathophysiology of hemophilia.- 2. Genetics of Hemophilia A and B.- 3. Inhibitors in Hemophilia A.- 4. Immune Tolerance In Patients with Hemophilia A.- 5. Hemophilia A: New drugs.- 6. Inhibitors in Hemophilia B.- 7. Immune Tolerance Induction in Hemophilia B.- 8. Hemophilia B: New Drugs.- 9. Management of Hemophilia Carriers.- 10. Pharmacoeconomic Aspects in Hemophilia.- 11. Assessment of Joint Health and Outcome Measures in Hemophilia.- 12. Musculoskeletal Medicine in Hemophilia.- 13. Management of Acute Hemarthrosis in Hemophilia (Including Joint Aspiration).- 14. Hemophilic Arthropathy: Radiosynovectomy.- 15. Hemophilic Arthropathy: Arthroscopic Joint Debridement.- 16. Hemophilic Arthropathy: Total Joint Arthroplasty.- 17. Hemophilic Arthropathy: Other Orthopedic Procedures.- 18. Gene Therapy in Hemophilia: Latest Advances.- 19.A Summary of the Recent Recommendations of the WFH.
Details
Erscheinungsjahr: 2022
Fachbereich: Andere Fachgebiete
Genre: Mathematik, Medizin, Naturwissenschaften, Technik
Rubrik: Wissenschaften
Medium: Buch
Inhalt: viii
173 S.
11 s/w Illustr.
31 farbige Illustr.
173 p. 42 illus.
31 illus. in color.
ISBN-13: 9783030939892
ISBN-10: 3030939898
Sprache: Englisch
Ausstattung / Beilage: HC runder Rücken kaschiert
Einband: Gebunden
Redaktion: Rodríguez-Merchán, E. Carlos
Herausgeber: E Carlos Rodríguez-Merchán
Auflage: 1st ed. 2022
Hersteller: Springer International Publishing
Springer International Publishing AG
Verantwortliche Person für die EU: Books on Demand GmbH, In de Tarpen 42, D-22848 Norderstedt, info@bod.de
Maße: 260 x 183 x 16 mm
Von/Mit: E. Carlos Rodríguez-Merchán
Erscheinungsdatum: 23.04.2022
Gewicht: 0,596 kg
Artikel-ID: 120855741
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