Charles E. Dean, M.D., has 47 years of clinical, educational, and research experience. He has taught psychopharmacology and clinical neuroscience at the Minneapolis VA Medical Center and the University of Minnesota.

List of Abbreviations; Permissions; Introduction; Chapter 1. The Biological Revolution in Psychiatry: An Overview of the Dark Ages; Chapter 2. The Biological Revolution: The Middle Years and the Rise of Psychopharmacology; Chapter 3. Has the Biological Revolution Delivered? A Focus on Antipsychotics; Chapter 4. Antipsychotics and the Metabolic Syndrome, Cardiovascular Disease, and Mortality; Chapter 5. Antipsychotics and Mortality in the Elderly with Dementia; Chapter 6. Psychotropic and Antipsychotic Polypharmacy: Common Practice, Good Medicine?; Chapter 7. The Neurologic Consequences of Antipsychotics: From Parkinsonism to Tardive Dyskinesia; Chapter 8. Antidepressants and Depression: Background and Biology; Chapter 9. Antidepressants: Do They Work? If So, When, How Often, and at What Costs?; Chapter 10. Antidepressants and Adverse Events: Falls and Fractures, Vascular Events, Risks in Pregnancy, and Abnormal Movements; Chapter 11. Treatment-Resistant Depression: Combining and Switching Antidepressants, Adding Antipsychotics, and On to Neurotherapeutics; Chapter 12. Desperately Treating Depression: On Psychotogenic and Hallucinogenic Drugs, Anti-Inflammatories, Antidiabetics, Hyperthermia, and Opioids; Chapter 13. Psychiatric Diagnoses: The DSM and the Roots of Failure; Chapter 14. Fear and Loathing at the APA: The DSM-5, The Brain Mapping Quartet, and the Future of Mental Illness; Index.