Frank E. Harrell, Jr. is Professor of Biostatistics and Chair, Department of Biostatistics, Vanderbilt University School of Medicine, Nashville. He has developed numerous methods for predictive modeling, quantifying predictive accuracy and model validation and has published numerous predictive models and articles on applied statistics, medical research and clinical trials. He is on the editorial board for several biomedical and methodologic journals. He is a Fellow of the American Statistical Association (ASA) and a consultant to the U.S. Food and Drug Administration and to the pharmaceutical industry. He teaches a graduate course in regression modeling strategies and a course in biostatistics for medical researchers. In 2014 he was chosen to receive the WJ Dixon Award for Excellence in Statistical Consulting by the ASA.

Fully revised new edition features new material and color figures

Published with mature, supplementary R package: rms

New chapters and sections on generalized least squares for analysis of serial response data, redundancy analysis, bootstrap confidence intervals for rankings of predictors, expanded material on multiple imputation and predictive mean matching and more

Includes supplementary material: [...]

Introduction.- General Aspects of Fitting Regression Models.- Missing Data.- Multivariable Modeling Strategies.- Describing, Resampling, Validating and Simplifying the Model.- R Software.- Modeling Longitudinal Responses using Generalized Least Squares.- Case Study in Data Reduction.- Overview of Maximum Likelihood Estimation.- Binary Logistic Regression.- Binary Logistic Regression Case Study 1.- Logistic Model Case Study 2: Survival of Titanic Passengers.- Ordinal Logistic Regression.- Case Study in Ordinal Regression, Data Reduction and Penalization.- Regression Models for Continuous Y and Case Study in Ordinal Regression.- Transform-Both-Sides Regression.- Introduction to Survival Analysis.- Parametric Survival Models.- Case Study in Parametric Survival Modeling and Model Approximation.- Cox Proportional Hazards Regression Model.- Case Study in Cox Regression.- Appendix.