Pathogenesis of Idiopathic Scoliosis

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Beschreibung

This book provides comprehensive coverage of current topics in idiopathic scoliosis (IS). A three-dimensional deformity of the spine, the condition is characterized by lateral curvature combined with vertebral rotation. The primary lesion, however, lies in the median sagittal plane, taking the form of a lordosis. Although the clinical manifestations of scoliosis have been well documented, its cause and pathogenesis have not yet been determined. Research into what causes IS has focused on the structural elements of the spine, spinal musculature, collagenous structures, the endocrine system, the central nervous system, and genetics. Results of these studies have brought about a new perception of IS epiphenomena, but the main cause of IS remains unknown. Recently, several investigators have produced new hypotheses regarding the cause of IS using the developing techniques of genetics, biochemistry, and neurology. This book is a review of the various causative factors thus far proposed forIS and an introduction to the directions in which research is heading to determine the primary cause of IS.

Über den Autor

Masafumi Machida, M.D.:

Director of National Institute of Musculo-Skeletal Disorders

Stuart L. Weinstein,M.D.:

Ignacio V. Ponseti Chair of Ortopaedic Surgery, Department of Orthopaedic Surgery University of Iowa Health Cara

Jean Dubousset,M.D.:

Academie Nationale de Medecine

Zusammenfassung

Presents the most current clinical and experimental topics in idiopathic scoliosis (IS)

Describes the variety of fields in which research into IS is being carried out

Provides useful insights into IS from leading specialists around the world

Inhaltsverzeichnis

1. Definition of Adolescent Idiopathic Scoliosis.-

2. Adolescent Idiopathic Scoliosis: Natural History.-

[...] Genetic Architecture of Adolescent Idiopathic Scoliosis.-

4. Biomechanics of Adolescent Idiopathic Scoliosis.-

5. Biochemistry of Idiopathic Scoliosis: From Discovery to Diagnostic Biomarkers.-

6. Bone Metabolism in AIS.-

7. Neurological Research in Idiopathic Scoliosis.

Details

Erscheinungsjahr:	2018
Fachbereich:	Andere Fachgebiete
Genre:	Importe , Medizin
Rubrik:	Wissenschaften
Medium:	Buch
Inhalt:	ix 188 S. 17 s/w Illustr. 21 farbige Illustr. 188 p. 38 illus. 21 illus. in color.
ISBN-13:	9784431565390
ISBN-10:	4431565396
Sprache:	Englisch
Herstellernummer:	978-4-431-56539-0
Ausstattung / Beilage:	HC runder Rücken kaschiert
Einband:	Gebunden
Redaktion:	Machida, Masafumi Dubousset, Jean Weinstein, Stuart L.
Herausgeber:	Masafumi Machida/Stuart L Weinstein/Jean Dubousset
Auflage:	1st ed. 2018
Hersteller:	Springer Japan Springer Japan KK
Verantwortliche Person für die EU:	Springer Verlag GmbH, Tiergartenstr. 17, D-69121 Heidelberg, juergen.hartmann@springer.com
Maße:	241 x 160 x 16 mm
Von/Mit:	Masafumi Machida (u. a.)
Erscheinungsdatum:	15.03.2018
Gewicht:	0,507 kg

Artikel-ID: 111054375