Includes cutting-edge methods and protocols for the manipulation of mitochondrial function

Provides step-by-step detail essential for reproducible results

Contains key notes and implementation advice from the experts

DQAsomes as the Prototype of Mitochondria-targeted Pharmaceutical Nanocarriers: Preparation, Characterization, and Use.- Predicting Mitochondrial Targeting by Small Molecule Xenobiotics Within Living Cells Using QSAR Models.- Targeting Mitochondria with Small Molecules: The Preparation of MitoB and MitoP as Exomarkers of Mitochondrial Hydrogen Peroxide.- Synthesis of Triphenylphosphonium Phospholipid Conjugates for the Preparation of Mitochondriotropic Liposomes.- Synthesis and Evaluation of
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F-Labeled Fluoroalkyl Triphenylphosphonium Salts as Mitochondrial Voltage Sensors in PET Myocardial Imaging.- Bridging the Gap Between Nature and Antioxidant Setbacks: Delivering Caffeic Acid to Mitochondria.- Mitochondriotropic Nano-Emulsified Genistein-Loaded Vehicles for Cancer Therapy.- Formulation and Optimization of Mitochondria-Targeted Polymeric Nanoparticles.- Ex Vivo Generation of Functional Immune Cells by Mitochondria-Targeted Photosensitization of Cancer Cells.- Targeting the Mitochondrial Genome Via a Dual Function MITO-Porter: Evaluation of mtDNA-Levels and Mitochondrial Function.- Mitochondrial, Acidic, and Cytosolic pHs Determination by
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P NMR Spectroscopy: Design of New Sensitive Targeted pH Probes.- Methodology for Use of Mitochondria-Targeted Cations in the Field of Oxidative Stress-Related Research.- Synthesis and Testing of Novel Isomeric Mitochondriotropic Derivatives of Resveratrol and Quercetin.- Evaluation of Respiration of Mitochondria in Cancer Cells Exposed to Mitochondria-Targeted Agents.- The Effect of Mitochondrially Targeted Anti-Cancer Agents on Mitochondrial (Super)Complexes.- Mitochondrial Targeting of Recombinant RNA.- Mitochondrial Targeting of Catalytic RNAs.- Allotopic Expression of ATP6 in the Mouse as a Transgenic Model of Mitochondrial Disease.- Analysis of Pollutant-InducedChanges in Mitochondrial DNA Methylation.- ETS and DEAS Studies of the Reduction of Xenobiotics in Mitochondrial Intermembrane Space.- Analysis of Mitochondrial Morphology and Function Under Conditions of Mitofusin 2 Deficiency.- Yeast as a Tool to Study Mitochondrial Retrograde Pathway En Route to Cell Stress Response.- Cell Energy Budget Platform for Assessment of Cell Metabolism.- Induced Pluripotent Stem Cells (iPSCs) for Modeling Mitochondrial DNA Disorders.- Cytoplasmic Transfer Methods for Studying the Segregation of Mitochondrial DNA in Mice.- In Vivo Visualization and Quantification of Mitochondrial Morphology in C. elegans.- Mitochondrial DNA as a Biosensor of UV Exposure in Human Skin.- Assessment of Short- and Medium-Chain Fatty Acids on Mitochondrial Function in Severe Inflammation.- Atomic Force Microscopy-Based Shape Analysis of Heart Mitochondria.- Enzymatic Assays for Probing Mitochondrial Apoptosis.- A Cybrid Cell Model for the Assessment of the Link Between Mitochondrial Deficits and Sporadic Parkinson's Disease.- Analysis of Mitochondrial Network by Imaging: Proof of Technique in Schizophrenia.