I. Preface From the Editor's Desk

II. Microbiome and Human Health: An Introduction 1. Oral Microbiome: A Gateway to Human Health 2. Influence of Microbiome in Shaping the Newborn Immune System: An Overview 3. Impact of Gut Bacteria on Human Health and Diseases 4. Individual Microbiota Correction and Human Health: Programing and Reprogramming of Systemic and Local Immune Response

III. Microbiome and Digestive Health 5. The Etiology of Gut Dysbiosis and its Role in Chronic Disease 6. Role of Microbiome in the Function and Diseases of the Digestive System

IV. Microbiome and Metabolic Syndrome 7. Beneficial Role of Healthy Microbiome in Metabolic Syndrome, Obesity and Cardiovascular Health 8. The Role of the Intestinal Microbiota in Weight Loss 9. Role of Microbial Metabolites in Cardiovascular and Human Health 10. Healthy Microbiome in Metabolic Syndrome, Obesity and Cardiovascular Health: An Overview 11. Potential Role of Healthy Microbiome in Metabolic Syndrome, Obesity and Cardiovascular Health 12. Restoring Gut Biome Balance for Weight Loss: Clinical applications 13. Harnessing Gut Friendly Microbiomes to Combat Metabolic Syndrome 14. The Effect of Resveratrol-Mediated Gut Microbiota Remodeling on Metabolic Disorders

V. Microbiome and Immune Health 15. Microbiome, Immunity, Anaerobism, and Inflammatory Conditions: A Multifaceted Systems Biology Intervention 16. Preclinical Data Supports the Strong Specificity and Advertised Ability to Mitigate Immune Reactions at Mucosal Sites VI. Microbiome and Cognitive Health 17. Achieving Dopamine Homeostasis to Combat Brain-Gut Functional Impairment: Behavioral and Neurogenetic Correlates of Reward Deficiency Syndrome (RDS) 18. Influence of Gut Microbial Flora in Body's Serotonin Turnover and Its Associated Diseases 19. The Connection Between Diet, Gut Microbes and Cognitive Decline 20. Role of the Gut Microbiome in Rett Syndrome

VII. Microbiome, Dermal Health and Wound Healing 21. Skin Microbiota and its Role in Health and Disease with an Emphasis in Chronic Wound Development and Wound Healing

VIII. Microbiome and Cancer 22. Healthy Gut Microbiome in the Prevention of Colorectal Cancer

IX. Microbiome, Arthritis and Multiple Sclerosis 23. Regulatory Roles of the Microbiome in Arthritis, Fibromyalgia, and Multiple Sclerosis

X. Environmental Pollutants and Gut Microbiome 24. Microplastic Exposure and Gut Microbiome

XI. Molecular and Immunological Mechanisms Associated with Healthy Gut Microbiome Functions 25. Role of the Gut Microbiome and Probiotics for Tuberculosis Prevention and Management 26. Lactic Acid Bacteria-Based Beverages in Promotion of Gastrointestinal Health 27. Prospective role of prebiotics and probiotics on gut immunity 28. Gut Brain Communication: A novel application of Probiotics 29. Beneficial Effects of Flaxseed on Gut Microbiota 30. Dietary Flavonoids and Gut Microbiota 31. Role of Mushroom Polysaccharides in Improving Gut health and Prevent Associated Diseases

XII. Microbiome and Immunomodulatory Peptides 32. Food derived immunomodulatory peptides: Science to applications

XIII. Study Design and Statistical Interpretation 33. Clinical Intervention Study Design and Statistical Methodology: Statistical Approaches for Pre-Post Studies

XIV. Commentary from the Editor's Desk 34. Conclusion and Editor's Commentary