Introduction

1-Introduction

II Molecules and cells

2 Amino Acids and Proteins

3- Carbohydrates and Lipids

4- Cells, Membranes and Transport.

III. Metabolism

5- Hemoglobin and oxygen transport.

6- Catalytic Proteins - Enzymes

7- Coenzymes Vitamins and Minerals

8- Bioenergetics and Oxidative Metabolism

9- Anaerobic metabolism of glucose carbohydrates in the red blood cell

10-The Tricarboxylic Acid Cycle

11-Oxidative Metabolism of Lipids in Liver and Muscle

12- Biosynthesis and Storage of Carbohydrates in Liver and Muscle: Glycogen metabolism and gluconeogenesis

13- Biosynthesis and Storage of Fatty Acids

14-"Metabolism of cholesterol and steroids".

15- Biosynthesis and Degradation of Amino Acids

16- Biosynthesis and Degradation of Nucleotides.

17- Complex Carbohydrates: Glycoproteins.

18- Complex Lipids

19-The Extracellular Matrix.

IV Molecular basis of inheritance

20- Deoxyribonucleic Acid.

21- Ribonucleic Acid.

22- Protein Synthesis and Turnover.

23- Regulation of Gene Expression: Basic Mechanisms

24- Fundamentals of recombinant DNA technology, molecular hybridisation and cloning

25- Genomics, Proteomics and Metabolomics.

V Signalling and growth

26- Membrane Receptors and Signal Transduction

27- Neurotransmitters.

28- Biochemical Endocrinology.

29- Cellular Homeostasis: Cell Growth and Cancer.

30- Aging

VI. Fuels Nutrients and Minerals

31- Digestion and Absorption of Nutrients: The Gastrointestinal Tract.

32- Glucose Homeostasis and Fuel Metabolism: Diabetes Mellitus.

33- Nutrients and diets, malnutrition and obesity

34- Lipoprotein Metabolism and Atherogenesis.

VII. Specialized Tissues and Their Function.

35- The Role of Liver in Metabolism.

36- Kidney: Water and Electrolytes Homeostasis

37- Lung and the Regulation of Hydrogen Ion Concentration (Acid-Base Balance)

38- Energy Metabolism and Contraction Exercise

39- Bone Metabolism and Calcium Homeostasis.

40- Neurochemistry

VIII. Blood and immunity. Clinical biochemistry.

41- Blood and Plasma Proteins.

42- Haemostasis and Thrombosis.

43- Oxidative stress and inflammation.

44-The Immune Response: Innate and adaptive immunity.

Appendix - selected clinical laboratory reference ranges.

Index