Provides new insights into the pathophysiology of obesity

Deciphers the complex links to diabetes and its complications

Collects most recent information on new strategies for prevention and treatment of obesity and diabetes

Part I Obesity. Epidemiology of Obesity.- The Circadian Clock and Obesity.- Nutrition and Microbiome.- From Obesity to Diabetes: The Role of the Adipose Organ.- Targeting Epicardial Fat in Obesity and Diabetes Pharmacotherapy.- The Enteroendocrine System in Obesity.- Insights from Studies of White Adipose Tissue Using Single-Cell Approaches.- Obesity-Related Insulin Resistance: The Central Role of Adipose Tissue Dysfunction.- Obesity, Senescence, and Senolytics.- Obesity and Obstructive Sleep Apnea.- Part II Diabetes and Complications. Inter-Organ Crosstalk in the Development of Obesity-Associated Insulin Resistance.- Islet Inflammation and ß Cell Dysfunction in Type 2 Diabetes.- NAFLD and NASH: The Metabolically Diseased Liver.- Diabetic Kidney Disease: From Pathogenesis to Novel Treatment Possibilities.- Diabetic Peripheral Neuropathy.- Part III Lifestyle Modifications and Future Treatments. Weight Loss Strategies.- PhysicalActivity, Obesity and Weight Loss Maintenance.- Bariatric/Metabolic Surgery.- Drugs for Treating Obesity.- Novel Drugs for Diabetes Therapy.- Novel Approaches to Restore Pancreatic Beta-Cell Mass
and Function.- Precision Medicine and Obesity.- Targeting the Enteroendocrine System for Treatment of Obesity.