Konstantinos Fountas

University of Thessaly, Larissa, Greece

Eftychia Z. Kapsalaki

University of Thessaly, Larissa, Greece

Discusses all modern imaging and electrophysiological methodologies for the preoperative evaluation of patients with intrinsic brain tumors and/or medically intractable epilepsy

Explains how to incorporate all preoperatively acquired information into the surgical planning

Describes all available adjuvant treatment modalities for patients harboring intrinsic brain tumors

Preoperative Evaluation: Non-invasive Methods.-Neurological examination & semiology.- Interpretation of conventional anatomical MRI.- Interpretation of proton MR spectroscopic imaging?.- Fractional Anisotropy and Diffusion Tensor Imaging as preoperative tools.- Functional MRI.- Nuclear medicine as a preoperative tool.- PET CT/MRI as a preoperative tool.- Magneto-Encephalography and Magnetic Source Imaging as preoperative tools.- Surface Encephalography and video-Encephalography.- High-density Encephalography as preoperative tool.- Transcranial magnetic source stimulation as preoperative tool.- Preoperative neuropsychological evaluation.- Preoperative Evaluation: Invasive Methods.- Invasive Electroencephalography with subdural/depth electrodes.- Stereo-Encephalography.- Extra-operative cortical stimulation and mapping.- Surgical Management:General considerations.- Intraoperative electrophysiological monitoring.- Awake procedures for cortical/subcortical mapping and monitoring.- Postoperative evaluation and follow-up.- Surgical Management: Epilepsy Surgical Procedures.- Neocortical resections.- Anterior temporal lobectomy and amygdalo-hippocampectomy.- Selective amygdalo-hippocampectomy.- Multiple subpial transections.- Corpus callosotomy.- Hemisherotomy.- Vagus nerve stimulation.- Deep brain stimulation.- Cortical stimulation.- G-knife in epilepsy.- Cyberknife in epilepsy.- Novel focal treatment modalities in epilepsy.- Surgical Management: Intrinsic Tumor Surgical Procedures.- Surgical resection techniques of frontal lobe tumors.- Surgical resection techniques of temporal lobe tumors.- Surgical resection techniques of central area tumors.- Surgical resection techniques of parietal lobe tumors.- Surgical resection techniques of occipital lobe tumors.- Surgical resection techniques of insular tumors.- Adjuvant treatment for intrinsic brain tumors.- Local interstitial chemotherapy.- Local interstitialbrachytherapy.- External radiation therapy.- Adjuvant stereotactic radiosurgery.- Systematic chemotherapy in intrinsic brain tumors.- Novel adjuvant focal therapies.- Monitoring for tumor recurrence.- Management of tumor recurrence.