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Cover: 9783662644119 | Chemical Biology | and Drug Discovery | Marco F. Schmidt | Taschenbuch
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Chemical Biology
and Drug Discovery
Taschenbuch von Marco F. Schmidt
Sprache: Englisch

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Beschreibung
The focus of this textbook is on application, rather than pure knowledge transfer of the results of all chemical biological work (which would also be beyond the scope of a book). It gives the reader, through the specific selection of chemical biological techniques and concepts, the necessary tools to be able to develop new ways of thinking and thus new therapeutic options in the complex field of chemical biology and drug development. The stated aim of this book is to provide concrete solutions and inspiration to students, (post)graduate students, and experienced scientists at universities as well as in industry in their problems.

After an introduction to the problems addressed by chemical biology in drug discovery, the three levels of molecular biology dogma: DNA, RNA and proteins and their role as drug targets serve as the common thread of this book.

This book is a translation of the original German 1st edition Chemische Biologie by Marco F. Schmidt, published by Springer-Verlag GmbH Germany, part of Springer Nature in 2020. The translation was done with the help of artificial intelligence (machine translation by the service [...]). A subsequent human revision was done primarily in terms of content, so that the book will read stylistically differently from a conventional translation. Springer Nature works continuously to further the development of tools for the production of books and on the related technologies to support the authors.

The focus of this textbook is on application, rather than pure knowledge transfer of the results of all chemical biological work (which would also be beyond the scope of a book). It gives the reader, through the specific selection of chemical biological techniques and concepts, the necessary tools to be able to develop new ways of thinking and thus new therapeutic options in the complex field of chemical biology and drug development. The stated aim of this book is to provide concrete solutions and inspiration to students, (post)graduate students, and experienced scientists at universities as well as in industry in their problems.

After an introduction to the problems addressed by chemical biology in drug discovery, the three levels of molecular biology dogma: DNA, RNA and proteins and their role as drug targets serve as the common thread of this book.

This book is a translation of the original German 1st edition Chemische Biologie by Marco F. Schmidt, published by Springer-Verlag GmbH Germany, part of Springer Nature in 2020. The translation was done with the help of artificial intelligence (machine translation by the service [...]). A subsequent human revision was done primarily in terms of content, so that the book will read stylistically differently from a conventional translation. Springer Nature works continuously to further the development of tools for the production of books and on the related technologies to support the authors.

Inhaltsverzeichnis
Foreword.- Introduction.- Part I: Chemical Biology and Drug Development.- Chemical Biology - a Holistic Science.- Drug Development.- From Genomics to Chemical Biology.- Part II: DNA.- DNA - blueprint of proteins.- Genomic Variation.- Gene Therapy and Genome Editing.- Part III: RNA.- RNA - information and function carrier.- RNA Interference in Drug Development.- Part IV: Proteins.- Peptides & proteins.- Proteins as drug targets.- Chemical genomics - From target protein to drug.- From target protein to macromolecular drug - Biologics.- Chemical proteomics: From drug to target protein.- Chemical genetics: validation of drug target by elucidation of signaling pathway.- Chemical biology - Addressing new drug targets.
Details
Erscheinungsjahr: 2022
Fachbereich: Organische Chemie
Genre: Chemie
Rubrik: Naturwissenschaften & Technik
Medium: Taschenbuch
Originaltitel: Chemische Biologie
Inhalt: IX
223 S.
40 s/w Illustr.
100 farbige Illustr.
223 p. 140 illus.
100 illus. in color.
ISBN-13: 9783662644119
ISBN-10: 3662644118
Sprache: Englisch
Herstellernummer: 978-3-662-64411-9
Autor: Schmidt, Marco F.
Hersteller: Springer
Springer, Berlin
Springer Berlin Heidelberg
Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, D-69121 Heidelberg, juergen.hartmann@springer.com
Abbildungen: IX, 223 p. 140 illus., 100 illus. in color.
Maße: 240 x 170 x 15 mm
Von/Mit: Marco F. Schmidt
Erscheinungsdatum: 02.02.2022
Gewicht: 0,421 kg
Artikel-ID: 120642560
Inhaltsverzeichnis
Foreword.- Introduction.- Part I: Chemical Biology and Drug Development.- Chemical Biology - a Holistic Science.- Drug Development.- From Genomics to Chemical Biology.- Part II: DNA.- DNA - blueprint of proteins.- Genomic Variation.- Gene Therapy and Genome Editing.- Part III: RNA.- RNA - information and function carrier.- RNA Interference in Drug Development.- Part IV: Proteins.- Peptides & proteins.- Proteins as drug targets.- Chemical genomics - From target protein to drug.- From target protein to macromolecular drug - Biologics.- Chemical proteomics: From drug to target protein.- Chemical genetics: validation of drug target by elucidation of signaling pathway.- Chemical biology - Addressing new drug targets.
Details
Erscheinungsjahr: 2022
Fachbereich: Organische Chemie
Genre: Chemie
Rubrik: Naturwissenschaften & Technik
Medium: Taschenbuch
Originaltitel: Chemische Biologie
Inhalt: IX
223 S.
40 s/w Illustr.
100 farbige Illustr.
223 p. 140 illus.
100 illus. in color.
ISBN-13: 9783662644119
ISBN-10: 3662644118
Sprache: Englisch
Herstellernummer: 978-3-662-64411-9
Autor: Schmidt, Marco F.
Hersteller: Springer
Springer, Berlin
Springer Berlin Heidelberg
Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, D-69121 Heidelberg, juergen.hartmann@springer.com
Abbildungen: IX, 223 p. 140 illus., 100 illus. in color.
Maße: 240 x 170 x 15 mm
Von/Mit: Marco F. Schmidt
Erscheinungsdatum: 02.02.2022
Gewicht: 0,421 kg
Artikel-ID: 120642560
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