I Basic Concepts.- Biologic Rhythms from Biblical to Modern Times. A Preface.- Principles of Clinical Chronobiology.- II Mechanisms of Rhythms.- Cellular and Molecular Aspects of Circadian Oscillators: Models and Mechanisms for Biological Timekeeping.- The Suprachiasmatic Nucleus and Other Pacemakers.- Molecular and Genetic Aspects of Chronobiology.- Seasonal and Daily Control of Enzyme Synthesis and Activity by Circadian Clocks.- III Data Processing.- Data Processing in Chronobiological Studies.- IV Pharmacology and Toxicology.- Chronopharmacology.- Chronotoxicology.- Rhythms in Drug-Induced Teratogenesis.- V Child Development and Aging.- Chronobiology of Pregnancy and the Perinatal Time Span.- Patterns of Growth Hormone Release During Childhood and Adolescent Development in the Human.- Rhythms in Biochemical Variables Related to Bone and Their Regulating Hormones.- Biological Rhythms and Aging.- VI Physical and Mental Performance.- Chronobiology of Mental Performance.- Biological, Behavioral and Intellectual Activity Rhythms of the Child During Its Development in Different Educational Environments.- Chronobiology of Physical Performance and Sports Medicine.- VII Shift Work and Transmeridian Flights.- Night and Shift Work and Transmeridian and Space Flights.- VIII Sleep.- Chronobiology of Human Sleep and Sleep Disorders.- IX Psychiatry.- The Complex Circadian Pacemaker in Affective Disorders.- X Endocrine and Metabolic Functions.- Rhythmic and Non-Rhythmic Modes of Anterior Pituitary Hormone Release in Man.- Chronobiology of the Hypothalamic-Pituitary-Adrenal and Renin-Angiotensin-Aldosterone Systems.- Chronobiology of the Hypothalamic-Pituitary-Gonadal Axis in Men and Women.- Chronobiology of the Hypothalamic-Pituitary-Thyroid Axis.- The Pineal.- Chronobiology of Endocrine-Immune Interactions.- Chronobiology, Nutrition, and Diabetes Mellitus.- Endocrine and Neuroendocrine Axis Testing in Clinical Medicine: Evidence for Time Dependency.- XI Hepatobiliary System.- Biological Rhythms in Hepatic Drug Metabolism and Biliary Systems.- XII Gastrointestinal System.- Chronobiology of the Gastrointestinal System.- XIII Cardiovascular System.- Cardiovascular Chronobiology and Chronopharmacology.- Chronobiologic Blood Pressure Assessment from Womb to Tomb.- XIV Respiratory System.- Nocturnal Asthma: Mechanisms and Chronotherapy.- XV Renal Physiology and Pathology.- Renal Excretion: Rhythms in Physiology and Pathology.- XVI Inflammatory Reactions.- Inflammatory Reaction and Disease States.- XVII Immunology and Hematology.- Chronobiology of Immune Functions: Cellular and Humoral Aspects.....- Chronobiology of Circulating Blood Cells and Platelets.- Chronobiology of Human Bone Marrow.- Chronobiology of Polymorphonuclear Leukocyte Migration.- Chronobiology in Hemostastis.- XVIII Cell Proliferation and Cancer.- Normal and Abnormal Cell Proliferation in Mice Especially as It Relates to Cancer.- Chronobiology of Endocrine and Endocrine-Responsive Tumors.- Chronochemotherapy of Malignant Tumors: Temporal Aspects of Antineoplastic Drug Toxicity.- Immune System in Relation to Cancer.- Rhythms in Tumor Markers.- XIX Epidemiology.- Chronoepidemiology: Chronobiology and Epidemiology.- XX Laboratory Medicine.- Chronobiology in Laboratory Medicine.