David S. Chang, MD, MS is a Radiation Oncologist at the CHRISTUS St. Patrick Regional Cancer Center in Lake Charles, LA, USA.

Foster D. Lasley, MD is a Radiation Oncologist at GenesisCare in Rogers, AK.

Indra J. Das, PhD, FACR, FASTRO is a professor and vice chair at northwestern university Feinberg School of Medicine, Chicago.

Marc S. Mendonca, PhD is a Professor of Radiation Oncology & Medical and Molecular Genetics, and Director of Radiation and Cancer Biology at Indiana University School of Medicine.

Joseph R. Dynlacht, PhD is a Professor of Radiation Oncology & BIOCHEMISTRY AND MOLECULAR BIOLOGY at Indiana University School of Medicine.

Easy-to-read handbook covering the physics and biology of radiation therapy

Fully updated and includes four new chapters on MRI linac, proton beam radiotherapy, chemomodulation and immunomodulation of radiation in vitro and in vivo, and scholastic and deterministic late effects

Reviews topics included on the radiation oncology, medical dosimetry, and radiation therapy board exams

Presents concepts in a step-by-step format featuring mnemonics, cartoons, and rules of thumb

Part I: Radiation Therapy Physics.- Atomic and Nuclear Structure.- Radioactive Decay.- Properties and Production of Radiation.- Interactions of Electromagnetic Radiation with Matter.- Interactions of Particulate Radiation with Matter.- Quantification and Measurement of Dose.- Characteristics of Photon Beams.- Dosimetry of Photon Beams in Water.- Dosimetry of Photon Beams in a Patient.- Dosimetry of Electron Beams.- Physics and Dosimetry of Brachytherapy.- Advanced Treatment Planning for EBRT.- Linac Quality Assurance.- Radiation Protection and Safety.- Quality Management Program.- Special Topics: Hyperthermia and Computers.- MRI linac.- Proton Beam Radiotherapy.- Part II: Radiation Therapy Biology.- Molecular Biology and Signaling.- Cancer Genetic and Molecular Characteristics.- Molecular Mechanisms of DNA Damage and Repair.- Cell Death and Survival Assays.- Fractionated Radiation Survival Models.- Oxygen Effect, Relative Biological Effectiveness and Linear Energy Transfer.- Tumor Micro-environment.- Cell and Tissue Kinetics.- Acute Effects of Total Body Irradiation (TBI).- Normal Tissue Radiation Responses.- Therapeutic Ratio.- Combined Modality Therapy.- Biology of Brachytherapy, Particle Therapy, and Alternative Radiation Modalities.- Chemomodulation and Immunomodulation of Radiation In Vitro and In Vivo.- Hyperthermia.- Stochastic and deterministic Late Effects.- Radiation Effects in the Embryo and Fetus.- Appendix A: Glossary of Terms and Physical Constants.- Appendix B: List of Radionuclides for Radiotherapy and Imaging