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Bacteriophage Therapy
From Lab to Clinical Practice
Taschenbuch von Sanna Sillankorva (u. a.)
Sprache: Englisch

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Beschreibung
This volume details the experimental approaches suitable for isolating and characterizing bacteriophages to formulating bacteriophage medicinal products and clinical application. Chapters guide readers through regulatory compliance and safety aspects of bacteriophage therapy. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Authoritative and cutting-edge, Bacteriophage Therapy: From Lab to Clinical Practice aims to ensure successful results in the further study of this vital field.
This volume details the experimental approaches suitable for isolating and characterizing bacteriophages to formulating bacteriophage medicinal products and clinical application. Chapters guide readers through regulatory compliance and safety aspects of bacteriophage therapy. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Authoritative and cutting-edge, Bacteriophage Therapy: From Lab to Clinical Practice aims to ensure successful results in the further study of this vital field.
Zusammenfassung
Includes cutting-edge methods and protocols Provides step-by-step detail essential for reproducible results
Contains key notes and implementation advice from the experts
Inhaltsverzeichnis

Isolation of Bacteriophages for Fastidious Bacteria.- Isolation of Bacteriophages of the Anaerobic Bacteria Bacteroides.- Isolation of Bacteriophages for Clinically Relevant Bacteria.- In Vitro Activity against Planktonic and Biofilm Populations Assessed by Flow Cytometry.- Observation of Bacteriophage Ultrastructure by Cryo-electron Microscopy.- Bacteriophage Taxonomy: an Evolving Discipline.- Determination of the Bacteriophage Host Range - Culture Based Approach.- Recovery and Characterization of Bacteria Resisting Infection by Lytic Bacteriophage.- Guidelines to Compose an Ideal Bacteriophage Cocktail.- Interaction of Bacteriophages with Mammalian Cells.- In Vivo Bacteriophage Biodistribution.- Interaction of Bacteriophages with the Immune System: Induction of Bacteriophage-specific Antibodies.- Bacteriophage Treatment of Infected Diabetic Foot Ulcers.- Compassionate Use of Bacteriophage Therapy for Foot Ulcer Treatment as an Effective Step for Moving Toward Clinical Trials.- Bacteriophage Production in Bioreactors.- Computational Modelling of Bacteriophage Production for Process Optimization.- Methods for Bacteriophage Preservation.- Bacteriophage Production in Compliance with Regulatory Requirements.- Guidelines for Bacteriophage Product Certification.- Nano/micro Formulations for Bacteriophage Delivery.- Synthetic Biology to Engineer Bacteriophage Genomes.

Details
Erscheinungsjahr: 2018
Fachbereich: Allgemeines
Genre: Biologie, Importe
Rubrik: Naturwissenschaften & Technik
Thema: Lexika
Medium: Taschenbuch
Reihe: Methods in Molecular Biology
Inhalt: xi
303 S.
23 s/w Illustr.
34 farbige Illustr.
303 p. 57 illus.
34 illus. in color.
ISBN-13: 9781493984725
ISBN-10: 1493984721
Sprache: Englisch
Ausstattung / Beilage: Paperback
Einband: Kartoniert / Broschiert
Redaktion: Sillankorva, Sanna
Azeredo, Joana
Herausgeber: Joana Azeredo/Sanna Sillankorva
Auflage: Softcover reprint of the original 1st ed. 2018
Hersteller: Springer New York
Springer US, New York, N.Y.
Methods in Molecular Biology
Verantwortliche Person für die EU: Books on Demand GmbH, In de Tarpen 42, D-22848 Norderstedt, info@bod.de
Maße: 254 x 178 x 18 mm
Von/Mit: Sanna Sillankorva (u. a.)
Erscheinungsdatum: 30.08.2018
Gewicht: 0,598 kg
Artikel-ID: 115376609
Zusammenfassung
Includes cutting-edge methods and protocols Provides step-by-step detail essential for reproducible results
Contains key notes and implementation advice from the experts
Inhaltsverzeichnis

Isolation of Bacteriophages for Fastidious Bacteria.- Isolation of Bacteriophages of the Anaerobic Bacteria Bacteroides.- Isolation of Bacteriophages for Clinically Relevant Bacteria.- In Vitro Activity against Planktonic and Biofilm Populations Assessed by Flow Cytometry.- Observation of Bacteriophage Ultrastructure by Cryo-electron Microscopy.- Bacteriophage Taxonomy: an Evolving Discipline.- Determination of the Bacteriophage Host Range - Culture Based Approach.- Recovery and Characterization of Bacteria Resisting Infection by Lytic Bacteriophage.- Guidelines to Compose an Ideal Bacteriophage Cocktail.- Interaction of Bacteriophages with Mammalian Cells.- In Vivo Bacteriophage Biodistribution.- Interaction of Bacteriophages with the Immune System: Induction of Bacteriophage-specific Antibodies.- Bacteriophage Treatment of Infected Diabetic Foot Ulcers.- Compassionate Use of Bacteriophage Therapy for Foot Ulcer Treatment as an Effective Step for Moving Toward Clinical Trials.- Bacteriophage Production in Bioreactors.- Computational Modelling of Bacteriophage Production for Process Optimization.- Methods for Bacteriophage Preservation.- Bacteriophage Production in Compliance with Regulatory Requirements.- Guidelines for Bacteriophage Product Certification.- Nano/micro Formulations for Bacteriophage Delivery.- Synthetic Biology to Engineer Bacteriophage Genomes.

Details
Erscheinungsjahr: 2018
Fachbereich: Allgemeines
Genre: Biologie, Importe
Rubrik: Naturwissenschaften & Technik
Thema: Lexika
Medium: Taschenbuch
Reihe: Methods in Molecular Biology
Inhalt: xi
303 S.
23 s/w Illustr.
34 farbige Illustr.
303 p. 57 illus.
34 illus. in color.
ISBN-13: 9781493984725
ISBN-10: 1493984721
Sprache: Englisch
Ausstattung / Beilage: Paperback
Einband: Kartoniert / Broschiert
Redaktion: Sillankorva, Sanna
Azeredo, Joana
Herausgeber: Joana Azeredo/Sanna Sillankorva
Auflage: Softcover reprint of the original 1st ed. 2018
Hersteller: Springer New York
Springer US, New York, N.Y.
Methods in Molecular Biology
Verantwortliche Person für die EU: Books on Demand GmbH, In de Tarpen 42, D-22848 Norderstedt, info@bod.de
Maße: 254 x 178 x 18 mm
Von/Mit: Sanna Sillankorva (u. a.)
Erscheinungsdatum: 30.08.2018
Gewicht: 0,598 kg
Artikel-ID: 115376609
Sicherheitshinweis