Tommaso Gori MD is Director of the Heart Catheterization Laboratory at the Zentrum für Kardiologie in Mainz, Germany. He trained at the University of Siena, Italy and completed a PhD at the University of Toronto. He is a specialist in Internal Medicine and Cardiology, with particular research interests in endothelial (dys)function, mechanisms and effects of organic nitrates, physiology of the coronary circulation, oxidative stress, microcirculation and hemorheology, and clinical research interests in interventional cardiology and echocardiography.

Dr Gori is a winner of many international awards, including the American Heart Association S.A. Levine Young Investigator Award and American College of Cardiology Young Investigator Award, both in 2001. He is on the Editorial Boards of the European Heart Journal, World Heart Journal, and Clinical Hemorheology and Microcirculation. He has written numerous articles, textbook chapters and lectures and has extensive teaching experience at University Medical Center Mainz and University of Siena.

Massimo Fineschi MD is Medical Director of the Hemodynamics Unit at the University Hospital Santa Maria alle Scotte in Siena, Italy. He trained at the University of Siena, Italy, and completed his training in Cardiology in 1995 at the same institution.

His work has covered Elective and Urgent coronary angiography, Elective and Primary coronary angioplasty, Right and left heart catheterization and he has contributed to many research papers, and has spearheaded many trials.

Incorporates FFR tracings from different cases (simple to complex ones) are presented alongside other multimodality assessments (IVUS, OCT) to integrate functional and anatomical information

Represents an excellent image resource for FFR-guided percutaneous coronary interventions

Provides in-depth clinical instruction for all learning about this technique

Section I - Setting the Stage.- Setting the Stage: How To Perform FFR.- Section II - Clinical Cases.- Starting Easy: FFR in a High-Grade Stenosis.- Another Easy One: This Time in the Other Direction.- A False-Positive FFR.- A Negative FFR.- Reproducibility of the Result.- Decision-making in a Long Lesion: Full Metal Jacket or Spot Stenting?.- When the Pd/Pa Is Already Significant: A "Quick and Clean" FFR.- Contrast-induced Hyperemia and FFR: Slightly Slower But Still "Quick and Clean".- Reproducibility of FFR.- Long-term Repeatability of FFR: Twin Measurements with Two Years In-between.- A Positive FFR in the Absence of Visible Stenosis: Where Is the Problem?.- Instant Wave-free Ratio Assessment.- Simplifying One's Life: From Three-Vessel to One-Vessel Disease.-FFR to Determine Stent Length: When the Play Gets Tough.- Multiple Lesions, Multiple Measures.- Sequential Lesions and Bioresorbable Scaffolds.- FFR for a Lesion in the Left Main: None is So Blind As Those Who Will Not See.- Imaging of Ostial Lesions: How Reliable Is It?.- A Complex Left Main Disease.- Bifurcation Lesions: A Quicker Solution for Re-entry.- A Bifurcation with Surprise.- A Wire in Jail.- Mismatch Between Imaging and Functional Relevance of Coronary Stenoses: Seeing Is Not Believing.- FFR or IVUS for Small Vessels?.- Same IVUS, Same Vessel, Different FFR.- In-Stent Restenosis.- In-stent Restenosis with a Twist.- Using FFR to Detect Ischemia in Myocardial Bridge Lesions.- ACS-NSTEMI.- A Normal Fractional and Coronary Flow Reserve.- Impaired Fractional and Coronary Flow Reserve.- High-grade Epicardial Stenosis with Microvascular Compensation.- Threshold FFR, Impaired CFR, and IMR: Macrovascular or Microvascular Disease?.- Coronary Slow Flow in a Patient with Myocarditis.- A Complex Combination of Microvascular and MacrovascularDiseases.- The Impact of Venous Pressure on FFR: Do Diuretics Affect FFR?.- Decision-making in a Long Lesion: Full Metal Jacket or Spot Stenting?.- FFR in a Bypass.- Heart Failure: Really Idiopathic?