Provides a practical overview of neuromuscular pathology - muscle, nerve and skin biopsies and biopsy interpretation

Offers neurologists and trainees useful clinical and pathology pearls to facilitate their learning of neuromuscular pathology and management of a variety of myopathies and neuropathies

Features a variety of educational cases that demonstrate biopsy utilities, clinical and pathological correlations, and individual disease management

Part I: Introduction to Neuromuscular Pathology Evaluation.-1. Skeletal Muscle Biopsy Evaluation.-2. Peripheral Nerve Biopsy Evaluation.-3. Skin Biopsy with Cutaneous Nerve Fiber Evaluation.-Part II: Myopathy Cases.-4. A 20-year-old man with acute multi-organ failure and rhabdomyolysis.-5. A 45-year-old woman with proximal limb weakness and skin peeling on fingertips.-6. A 75-year-old man with leg and hand weakness.-7. A 53-year-old woman with proximal limb weakness and marked CK elevation.-8. A 61-year-old woman with distal limb and deltoid weakness.-9. A 63-year-old woman with debilitating muscle pain.-10. A 33-year-old woman with pain and swelling in the right calf and persistent fever.-11. A 28-year-old woman with proximal limb weakness and scapular winging.-12. A 52-year-old man with proximal limb weakness and hand stiffness.-13. A 51-year-old woman with long-standing exercise intolerance.-14. A 37-year-old woman with leg weakness.-15. A 25-year-old woman with droopy eyelids and double vision.-16. A 58-year-old man with hypercapnic respiratory failure.-17. A 65-year-old man with asymmetrical leg weakness and foot tingling.-18. A 40-year-old man with muscle pain and fatigue.-19. A 42-year-old woman with progressive limb weakness and breathing difficulty.-20. A 49-year-old man with limb weakness and skin changes.-21. A 54-year-old man with lower limb weakness.-22. A 63-year-old man with progressive limb weakness and slurred speech.-23. A 6-year-old girl with muscle pain and swelling in the thighs.-24. A 4-year-old boy with progressive weakness, difficulty walking and running, and increased falls.-25. A 2-year-old girl with hypotonia since birth and delayed motor and speech development.-26. An 8-year-old boy with delayed motor milestones and proximal leg muscle weakness.-27. A 6-year-old-boy with proximal leg muscle weakness and facial weakness.-28. A 6-week-old boy with neonatal hypotonia and feeding and respiratory difficulties.-29. A 6-year-old boy with respiratory and feeding difficulties at birth, delayed gross motor milestones, and facial and proximal lower limb weakness.-30. A 12-year-old girl with a 2-year history of progressive weakness and difficulties with exercise.-31. A 3-month-old boy with generalized hypotonia, weakness, pneumonia and respiratory failure.-Part III: Neuropathy Cases.-32. A 59-year-old woman with subacute lower limb weakness and painful paresthesia.-33. A 63-year-old man with nausea, vomiting, orthostatic dizziness, and distal limb paresthesia.-34. A 47-year-old woman with progressive numbness and weakness in the limbs.-35. A 65-year-old woman with acute limb weakness and worsening of paresthesia.-36. A 34-year-old man with right hand and left foot numbness.-37. A 64-year-old woman with progressive pain, numbness and weakness in the right lower limb.-38. A 68-year-old man with progressive lower limb numbness and weakness and urinary incontinence.-39. A 53-year-old woman with pain, burning, tingling, and numbnessin the distal limbs.-40. A 40-year-old woman with patchy painful paresthesia.-41. A 39-year-old woman with intermittent bilateral foot and leg pain since childhood.- 42. A 35-year-old man with pain and numbness in the left lateral thigh.